Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS

OBJECTIVE: To examine the safety and tolerability as well as the preliminary efficacy of arimoclomol, a heat shock protein co-inducer that promotes nascent protein folding, in patients with rapidly progressive SOD1 amyotrophic lateral sclerosis (ALS). METHODS: This was a double-blind, placebo-contro...

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Detalles Bibliográficos
Autores principales: Benatar, Michael, Wuu, Joanne, Andersen, Peter M., Atassi, Nazem, David, William, Cudkowicz, Merit, Schoenfeld, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818014/
https://www.ncbi.nlm.nih.gov/pubmed/29367439
http://dx.doi.org/10.1212/WNL.0000000000004960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818014/
https://www.ncbi.nlm.nih.gov/pubmed/29367439
http://dx.doi.org/10.1212/WNL.0000000000004960

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