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A CK1 FRET biosensor reveals that DDX3X is an essential activator of CK1ε

Casein kinase 1 (CK1) plays central roles in various signal transduction pathways and performs many cellular activities. For many years CK1 was thought to act independently of modulatory subunits and in a constitutive manner. Recently, DEAD box RNA helicases, in particular DEAD box RNA helicase 3 X-...

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Detalles Bibliográficos
Autores principales: Dolde, Christine, Bischof, Joachim, Grüter, Simon, Montada, Anna, Halekotte, Jakob, Peifer, Christian, Kalbacher, Hubert, Baumann, Ulrich, Knippschild, Uwe, Suter, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818060/
https://www.ncbi.nlm.nih.gov/pubmed/29222110
http://dx.doi.org/10.1242/jcs.207316