High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation

The human Ras superfamily of small GTPases controls essential cellular processes such as gene expression and cell proliferation. As their deregulation is widely associated with human cancer, small GTPases and their regulatory proteins have become increasingly attractive for the development of novel...

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Detalles Bibliográficos
Autores principales: Koraïchi, Faten, Gence, Rémi, Bouchenot, Catherine, Grosjean, Sarah, Lajoie-Mazenc, Isabelle, Favre, Gilles, Cabantous, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Tools and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818064/
https://www.ncbi.nlm.nih.gov/pubmed/29192060
http://dx.doi.org/10.1242/jcs.210419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818064/
https://www.ncbi.nlm.nih.gov/pubmed/29192060
http://dx.doi.org/10.1242/jcs.210419

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