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High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation
The human Ras superfamily of small GTPases controls essential cellular processes such as gene expression and cell proliferation. As their deregulation is widely associated with human cancer, small GTPases and their regulatory proteins have become increasingly attractive for the development of novel...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818064/ https://www.ncbi.nlm.nih.gov/pubmed/29192060 http://dx.doi.org/10.1242/jcs.210419 |