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NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo

In mitosis, the molecular motor dynein is recruited to kinetochores by the Rod–Zw10–Zwilch complex (RZZ) and Spindly to control spindle assembly checkpoint (SAC) signaling and microtubule attachment. How the ubiquitous dynein co-factors Lis1 and NudE contribute to these functions remains poorly unde...

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Detalles Bibliográficos
Autores principales: Simões, Patrícia A., Celestino, Ricardo, Carvalho, Ana X., Gassmann, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818066/
https://www.ncbi.nlm.nih.gov/pubmed/29192061
http://dx.doi.org/10.1242/jcs.212159