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NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo
In mitosis, the molecular motor dynein is recruited to kinetochores by the Rod–Zw10–Zwilch complex (RZZ) and Spindly to control spindle assembly checkpoint (SAC) signaling and microtubule attachment. How the ubiquitous dynein co-factors Lis1 and NudE contribute to these functions remains poorly unde...
Autores principales: | Simões, Patrícia A., Celestino, Ricardo, Carvalho, Ana X., Gassmann, Reto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818066/ https://www.ncbi.nlm.nih.gov/pubmed/29192061 http://dx.doi.org/10.1242/jcs.212159 |
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