Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

We previously identified dipeptidylpeptidase 10 (DPP10) on chromosome 2 as a human asthma susceptibility gene, through positional cloning. Initial association results were confirmed in many subsequent association studies but the functional role of DPP10 in asthma remains unclear. Using the MRC Harwe...

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Detalles Bibliográficos
Autores principales: Zhang, Youming, Poobalasingam, Thanushiyan, Yates, Laura L., Walker, Simone A., Taylor, Martin S., Chessum, Lauren, Harrison, Jackie, Tsaprouni, Loukia, Adcock, Ian M., Lloyd, Clare M., Cookson, William O., Moffatt, Miriam F., Dean, Charlotte H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818078/
https://www.ncbi.nlm.nih.gov/pubmed/29361513
http://dx.doi.org/10.1242/dmm.031369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818078/
https://www.ncbi.nlm.nih.gov/pubmed/29361513
http://dx.doi.org/10.1242/dmm.031369

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