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Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host

Studying the complex mechanisms underlying breast cancer metastasis and therapy response necessitates relevant in vivo models, particularly syngeneic models with an intact immune system. Two syngeneic spontaneously metastatic sublines, D2A1-m1 and D2A1-m2, were generated from the poorly metastasisin...

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Detalles Bibliográficos
Autores principales: Jungwirth, Ute, van Weverwijk, Antoinette, Melake, Miriam J., Chambers, Ann F., Gao, Qiong, Fivaz, Marc, Isacke, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818081/
https://www.ncbi.nlm.nih.gov/pubmed/29208627
http://dx.doi.org/10.1242/dmm.031740