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Adjunct zonisamide to levodopa for DLB parkinsonism: A randomized double-blind phase 2 study

OBJECTIVE: To investigate the efficacy and safety of zonisamide as an adjunct to levodopa therapy for parkinsonism in patients with dementia with Lewy bodies (DLB). METHODS: This phase 2, placebo-controlled, randomized, double-blind study consisted of run-in (placebo, 4 weeks) and treatment (placebo...

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Detalles Bibliográficos
Autores principales: Murata, Miho, Odawara, Toshinari, Hasegawa, Kazuko, Iiyama, Sayaka, Nakamura, Masatoshi, Tagawa, Masaaki, Kosaka, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818167/
https://www.ncbi.nlm.nih.gov/pubmed/29367449
http://dx.doi.org/10.1212/WNL.0000000000005010