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Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

Increasing evidence has linked dysregulated interleukin (IL)-10 production by IL-10(+ve) B cells to autoimmunity, highlighting the importance of improving the understanding of the regulation of IL-10 production in these cells. In both B cells and myeloid cells, IL-10 can be produced in response to T...

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Detalles Bibliográficos
Autores principales: Sutavani, Ruhcha V., Phair, Iain R., Barker, Rebecca, McFarlane, Alison, Shpiro, Natalia, Lang, Stuart, Woodland, Andrew, Arthur, J. Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818195/
https://www.ncbi.nlm.nih.gov/pubmed/29229781
http://dx.doi.org/10.1074/jbc.M117.805424