Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres

Pulmonary fibrosis is a fatal lung disease characterized by fibrotic foci and inflammatory infiltrates. Short telomeres can impair tissue regeneration and are found both in hereditary and sporadic cases. We show here that telomerase expression using AAV9 vectors shows therapeutic effects in a mouse...

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Detalles Bibliográficos
Autores principales: Povedano, Juan Manuel, Martinez, Paula, Serrano, Rosa, Tejera, Águeda, Gómez-López, Gonzalo, Bobadilla, Maria, Flores, Juana Maria, Bosch, Fátima, Blasco, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818250/
https://www.ncbi.nlm.nih.gov/pubmed/29378675
http://dx.doi.org/10.7554/eLife.31299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818250/
https://www.ncbi.nlm.nih.gov/pubmed/29378675
http://dx.doi.org/10.7554/eLife.31299

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