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Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
Pulmonary fibrosis is a fatal lung disease characterized by fibrotic foci and inflammatory infiltrates. Short telomeres can impair tissue regeneration and are found both in hereditary and sporadic cases. We show here that telomerase expression using AAV9 vectors shows therapeutic effects in a mouse...
Autores principales: | Povedano, Juan Manuel, Martinez, Paula, Serrano, Rosa, Tejera, Águeda, Gómez-López, Gonzalo, Bobadilla, Maria, Flores, Juana Maria, Bosch, Fátima, Blasco, Maria A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818250/ https://www.ncbi.nlm.nih.gov/pubmed/29378675 http://dx.doi.org/10.7554/eLife.31299 |
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