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The emerging role and targetability of the TCA cycle in cancer metabolism

The tricarboxylic acid (TCA) cycle is a central route for oxidative phosphorylation in cells, and fulfills their bioenergetic, biosynthetic, and redox balance requirements. Despite early dogma that cancer cells bypass the TCA cycle and primarily utilize aerobic glycolysis, emerging evidence demonstr...

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Detalles Bibliográficos
Autores principales: Anderson, Nicole M., Mucka, Patrick, Kern, Joseph G., Feng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818369/
https://www.ncbi.nlm.nih.gov/pubmed/28748451
http://dx.doi.org/10.1007/s13238-017-0451-1