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Engineered T Regulatory Type 1 Cells for Clinical Application

T regulatory cells, a specialized subset of T cells, are key players in modulating antigen (Ag)-specific immune responses in vivo. Inducible T regulatory type 1 (Tr1) cells are characterized by the co-expression of CD49b and lymphocyte-activation gene 3 (LAG-3) and the ability to secrete IL-10, TGF-...

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Detalles Bibliográficos
Autores principales: Gregori, Silvia, Roncarolo, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818395/
https://www.ncbi.nlm.nih.gov/pubmed/29497421
http://dx.doi.org/10.3389/fimmu.2018.00233