Cargando…

Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity

Bone metastasis in breast, prostate and lung cancers often leads to chronic pain, which is poorly managed by existing analgesics. The neurobiological mechanisms that underlie chronic pain associated with bone-metastasized cancers are not well understood, but sensitization of peripheral nociceptors b...

Descripción completa

Detalles Bibliográficos
Autores principales: Shepherd, Andrew J., Mickle, Aaron D., Kadunganattil, Suraj, Hu, Hongzhen, Mohapatra, Durga P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818411/
https://www.ncbi.nlm.nih.gov/pubmed/29497363
http://dx.doi.org/10.3389/fncel.2018.00038