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Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity
Bone metastasis in breast, prostate and lung cancers often leads to chronic pain, which is poorly managed by existing analgesics. The neurobiological mechanisms that underlie chronic pain associated with bone-metastasized cancers are not well understood, but sensitization of peripheral nociceptors b...
Autores principales: | Shepherd, Andrew J., Mickle, Aaron D., Kadunganattil, Suraj, Hu, Hongzhen, Mohapatra, Durga P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818411/ https://www.ncbi.nlm.nih.gov/pubmed/29497363 http://dx.doi.org/10.3389/fncel.2018.00038 |
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