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Reduced Orbitofrontal Gray Matter Concentration as a Marker of Premorbid Childhood Trauma in Cocaine Use Disorder

Background: Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and cognitive control may be an underlying substrate, as docume...

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Detalles Bibliográficos
Autores principales: Bachi, Keren, Parvaz, Muhammad A., Moeller, Scott J., Gan, Gabriela, Zilverstand, Anna, Goldstein, Rita Z., Alia-Klein, Nelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818418/
https://www.ncbi.nlm.nih.gov/pubmed/29497369
http://dx.doi.org/10.3389/fnhum.2018.00051