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Reduced Orbitofrontal Gray Matter Concentration as a Marker of Premorbid Childhood Trauma in Cocaine Use Disorder
Background: Childhood trauma affects neurodevelopment and promotes vulnerability to impaired constraint, depression, and addiction. Reduced gray matter concentration (GMC) in the mesocorticolimbic regions implicated in reward processing and cognitive control may be an underlying substrate, as docume...
Autores principales: | Bachi, Keren, Parvaz, Muhammad A., Moeller, Scott J., Gan, Gabriela, Zilverstand, Anna, Goldstein, Rita Z., Alia-Klein, Nelly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818418/ https://www.ncbi.nlm.nih.gov/pubmed/29497369 http://dx.doi.org/10.3389/fnhum.2018.00051 |
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