Anti-inflammatory Mechanism of Geniposide: Inhibiting the Hyperpermeability of Fibroblast-Like Synoviocytes via the RhoA/p38MAPK/NF-κB/F-Actin Signal Pathway

Geniposide (GE) is the extraction and purification of iridoid glycosides from the Gardenia jasminoides Ellis, which is a promising anti-inflammatory drug, but its mechanism of actions on rheumatoid arthritis (RA) has not been clarified. This study investigated the molecular mechanism behind GE reduc...

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Detalles Bibliográficos
Autores principales: Deng, Ran, Li, Feng, Wu, Hong, Wang, Wen-yu, Dai, Li, Zhang, Zheng-rong, Fu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818421/
https://www.ncbi.nlm.nih.gov/pubmed/29497378
http://dx.doi.org/10.3389/fphar.2018.00105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818421/
https://www.ncbi.nlm.nih.gov/pubmed/29497378
http://dx.doi.org/10.3389/fphar.2018.00105

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