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Anti-inflammatory Mechanism of Geniposide: Inhibiting the Hyperpermeability of Fibroblast-Like Synoviocytes via the RhoA/p38MAPK/NF-κB/F-Actin Signal Pathway
Geniposide (GE) is the extraction and purification of iridoid glycosides from the Gardenia jasminoides Ellis, which is a promising anti-inflammatory drug, but its mechanism of actions on rheumatoid arthritis (RA) has not been clarified. This study investigated the molecular mechanism behind GE reduc...
Autores principales: | Deng, Ran, Li, Feng, Wu, Hong, Wang, Wen-yu, Dai, Li, Zhang, Zheng-rong, Fu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818421/ https://www.ncbi.nlm.nih.gov/pubmed/29497378 http://dx.doi.org/10.3389/fphar.2018.00105 |
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