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Transcriptional and translational‐uncoupling in regulation of the CXCL12 and its receptors CXCR4, 7 in THP‐1 monocytes and macrophages

INTRODUCTION: The chemokine CXCL12 and its receptors CXCR4 and 7 play crucial roles in the immune system. In the present study, regulation of this pathway was further examined using the in‐vitro model of undifferentiated human THP‐1 monocytes (u‐THP‐1) and phorbol 12‐myristate 13‐acetate (PMA)‐diffe...

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Detalles Bibliográficos
Autores principales: Yu, Lu, Yu, Liangli, Pham, Quynhchi, Wang, Thomas T. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818454/
https://www.ncbi.nlm.nih.gov/pubmed/29105376
http://dx.doi.org/10.1002/iid3.199