In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum

The Plasmodium falciparum variant surface antigen PfEMP1 expressed on the surface of infected erythrocytes is thought to play a major role in the pathology of severe malaria. As the sequence pool of the var genes encoding PfEMP1 expands there are opportunities, despite the high degree of sequence di...

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Detalles Bibliográficos
Autores principales: Carrington, Eilidh, Otto, Thomas D., Szestak, Tadge, Lennartz, Frank, Higgins, Matt K., Newbold, Chris I., Craig, Alister G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818487/
https://www.ncbi.nlm.nih.gov/pubmed/29459671
http://dx.doi.org/10.1038/s41598-018-21591-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818487/
https://www.ncbi.nlm.nih.gov/pubmed/29459671
http://dx.doi.org/10.1038/s41598-018-21591-8

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