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In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum
The Plasmodium falciparum variant surface antigen PfEMP1 expressed on the surface of infected erythrocytes is thought to play a major role in the pathology of severe malaria. As the sequence pool of the var genes encoding PfEMP1 expands there are opportunities, despite the high degree of sequence di...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818487/ https://www.ncbi.nlm.nih.gov/pubmed/29459671 http://dx.doi.org/10.1038/s41598-018-21591-8 |