Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance

Microtubules are highly dynamic structures that form spindle fibres during mitosis and are one of the most validated cancer targets. The success of drugs targeting microtubules, however, is often limited by the development of multidrug resistance. Here we describe the discovery and characterization...

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Detalles Bibliográficos
Autores principales: Manzoor, Safia, Bilal, Aishah, Khan, Sardraz, Ullah, Rahim, Iftikhar, Sunniya, Emwas, Abdul-Hamid, Alazmi, Meshari, Gao, Xin, Jawaid, Ali, Saleem, Rahman Shah Zaib, Faisal, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818492/
https://www.ncbi.nlm.nih.gov/pubmed/29459693
http://dx.doi.org/10.1038/s41598-018-21642-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818492/
https://www.ncbi.nlm.nih.gov/pubmed/29459693
http://dx.doi.org/10.1038/s41598-018-21642-0

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