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Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance
Microtubules are highly dynamic structures that form spindle fibres during mitosis and are one of the most validated cancer targets. The success of drugs targeting microtubules, however, is often limited by the development of multidrug resistance. Here we describe the discovery and characterization...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818492/ https://www.ncbi.nlm.nih.gov/pubmed/29459693 http://dx.doi.org/10.1038/s41598-018-21642-0 |