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Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

In chronic infections, bacterial pathogens typically grow as small dense cell aggregates embedded in a matrix consisting of, e.g., wound bed sludge or lung mucus. Such biofilm growth mode exhibits extreme tolerance towards antibiotics and the immune defence system. The bacterial aggregates are expos...

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Detalles Bibliográficos
Autores principales: Sønderholm, Majken, Koren, Klaus, Wangpraseurt, Daniel, Jensen, Peter Østrup, Kolpen, Mette, Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Kühl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818519/
https://www.ncbi.nlm.nih.gov/pubmed/29479470
http://dx.doi.org/10.1038/s41522-018-0047-4