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Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model
In chronic infections, bacterial pathogens typically grow as small dense cell aggregates embedded in a matrix consisting of, e.g., wound bed sludge or lung mucus. Such biofilm growth mode exhibits extreme tolerance towards antibiotics and the immune defence system. The bacterial aggregates are expos...
Autores principales: | Sønderholm, Majken, Koren, Klaus, Wangpraseurt, Daniel, Jensen, Peter Østrup, Kolpen, Mette, Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Kühl, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818519/ https://www.ncbi.nlm.nih.gov/pubmed/29479470 http://dx.doi.org/10.1038/s41522-018-0047-4 |
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