A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells

Human exposure to carcinogens occurs via a plethora of environmental sources, with 70–90% of cancers caused by extrinsic factors. Aberrant phenotypes induced by such carcinogenic agents may provide universal biomarkers for cancer causation. Both current in vitro genotoxicity tests and the animal-tes...

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Detalles Bibliográficos
Autores principales: Wilde, Eleanor C., Chapman, Katherine E., Stannard, Leanne M., Seager, Anna L., Brüsehafer, Katja, Shah, Ume-Kulsoom, Tonkin, James A., Brown, M. Rowan, Verma, Jatin R., Doherty, Ann T., Johnson, George E., Doak, Shareen H., Jenkins, Gareth J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818597/
https://www.ncbi.nlm.nih.gov/pubmed/29110037
http://dx.doi.org/10.1007/s00204-017-2102-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818597/
https://www.ncbi.nlm.nih.gov/pubmed/29110037
http://dx.doi.org/10.1007/s00204-017-2102-y

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