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GABA(A) receptor subtype selectivity of the proconvulsant rodenticide TETS

The rodenticide tetramethylenedisulfotetramine (TETS) is a potent convulsant (lethal dose in humans 7–10 mg) that is listed as a possible threat agent by the United States Department of Homeland Security. TETS has previously been studied in vivo for toxicity and in vitro in binding assays, with the...

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Detalles Bibliográficos
Autores principales: Pressly, Brandon, Nguyen, Hai M., Wulff, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818616/
https://www.ncbi.nlm.nih.gov/pubmed/29038840
http://dx.doi.org/10.1007/s00204-017-2089-4