Cargando…

Towards the design of anti-amyloid short peptide helices

A set of short peptide sequences susceptible to fibrillar aggregation produces sequneces capable of arresting elongation of amyloid fibrils. The "stop" signals are short helices customized for each individual target. Such a helix should exhibit high amphiphilicity, with differing condition...

Descripción completa

Detalles Bibliográficos
Autores principales: Roterman, Irena, Banach, Mateusz, Konieczny, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818643/
https://www.ncbi.nlm.nih.gov/pubmed/29497253
http://dx.doi.org/10.6026/97320630014001