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Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling

BACKGROUND: CLCA2 was reported as a tumor suppressor and disregulated in breast cancer. However, its function in tumor growth and metastasis in NPC has rarely been reported. In this study, we investigated the functional and molecular mechanisms by which CLCA2 influences NPC. METHODS: CLCA2 expressio...

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Detalles Bibliográficos
Autores principales: Qiang, Yuan-Yuan, Li, Chang-Zhi, Sun, Rui, Zheng, Li-Sheng, Peng, Li-Xia, Yang, Jun-Ping, Meng, Dong-Fang, Lang, Yan-Hong, Mei, Yan, Xie, Ping, Xu, Liang, Cao, Yun, Wei, Wen-Wen, Cao, Li, Hu, Hao, Yang, Qin, Luo, Dong-Hua, Liang, Ying-Ying, Huang, Bi-Jun, Qian, Chao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819171/
https://www.ncbi.nlm.nih.gov/pubmed/29463274
http://dx.doi.org/10.1186/s13046-018-0692-8