C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance

BACKGROUND: Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure. The proto-oncogene c-fos has been shown to be involved in the development of MDR in several tumor...

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Detalles Bibliográficos
Autores principales: Li, Guodong, Hu, Xiaoling, Sun, Lu, Li, Xin, Li, Jianfeng, Li, Tongli, Zhang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819209/
https://www.ncbi.nlm.nih.gov/pubmed/29483928
http://dx.doi.org/10.1186/s11658-017-0067-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819209/
https://www.ncbi.nlm.nih.gov/pubmed/29483928
http://dx.doi.org/10.1186/s11658-017-0067-8

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