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Transgenerational effects of polychlorinated biphenyls: 1. Development and physiology across 3 generations of rats

BACKGROUND: Polychlorinated biphenyls (PCBs) are persistent organic environmental contaminants and known endocrine-disrupting chemicals (EDCs). Previous studies demonstrated that developmental exposure to the weakly estrogenic PCB mixture Aroclor 1221 (A1221) in Sprague-Dawley rats altered sexual de...

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Detalles Bibliográficos
Autores principales: Mennigen, Jan A., Thompson, Lindsay M., Bell, Mandee, Tellez Santos, Marlen, Gore, Andrea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819226/
https://www.ncbi.nlm.nih.gov/pubmed/29458364
http://dx.doi.org/10.1186/s12940-018-0362-5