Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells

BACKGROUND: Lymphotoxin (LT) is a lymphokine mainly expressed in lymphocytes. LTα binds one or two membrane-associated LTβ to form LTα(2)β(1) or LTα(1)β(2) heterotrimers. The predominant LTα(1)β(2) binds to LTβ receptor (LTβR) primarily expressed in epithelial and stromal cells. Most studies on LTβR...

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Detalles Bibliográficos
Autores principales: Xiao, Xiao, Putatunda, Raj, Zhang, Yonggang, Soni, Priya V., Li, Fang, Zhang, Ting, Xin, Mingyang, Luo, Jin Jun, Bethea, John R., Cheng, Yuan, Hu, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819232/
https://www.ncbi.nlm.nih.gov/pubmed/29463313
http://dx.doi.org/10.1186/s12974-018-1074-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819232/
https://www.ncbi.nlm.nih.gov/pubmed/29463313
http://dx.doi.org/10.1186/s12974-018-1074-z

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