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Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells
BACKGROUND: Mammalian embryonic stem cells display a unique epigenetic and transcriptional state to facilitate pluripotency by maintaining lineage-specification genes in a poised state. Two epigenetic and transcription processes involved in maintaining poised state are bivalent chromatin, characteri...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819258/ https://www.ncbi.nlm.nih.gov/pubmed/29458328 http://dx.doi.org/10.1186/s12861-018-0163-7 |