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Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells

BACKGROUND: Mammalian embryonic stem cells display a unique epigenetic and transcriptional state to facilitate pluripotency by maintaining lineage-specification genes in a poised state. Two epigenetic and transcription processes involved in maintaining poised state are bivalent chromatin, characteri...

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Detalles Bibliográficos
Autores principales:	Mantsoki, Anna, Devailly, Guillaume, Joshi, Anagha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819258/ https://www.ncbi.nlm.nih.gov/pubmed/29458328 http://dx.doi.org/10.1186/s12861-018-0163-7

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