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Molecular clutch drives cell response to surface viscosity

Cell response to matrix rigidity has been explained by the mechanical properties of the actin-talin-integrin-fibronectin clutch. Here the molecular clutch model is extended to account for cell interactions with purely viscous surfaces (i.e., without an elastic component). Supported lipid bilayers pr...

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Detalles Bibliográficos
Autores principales: Bennett, Mark, Cantini, Marco, Reboud, Julien, Cooper, Jonathan M., Roca-Cusachs, Pere, Salmeron-Sanchez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819391/
https://www.ncbi.nlm.nih.gov/pubmed/29358406
http://dx.doi.org/10.1073/pnas.1710653115