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Methyltransferases of gentamicin biosynthesis
Gentamicin C complex from Micromonospora echinospora remains a globally important antibiotic, and there is revived interest in the semisynthesis of analogs that might show improved therapeutic properties. The complex consists of five components differing in their methylation pattern at one or more s...
Autores principales: | Li, Sicong, Guo, Junhong, Reva, Anna, Huang, Fanglu, Xiong, Binbin, Liu, Yuanzhen, Deng, Zixin, Leadlay, Peter F., Sun, Yuhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819394/ https://www.ncbi.nlm.nih.gov/pubmed/29358400 http://dx.doi.org/10.1073/pnas.1711603115 |
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