Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells

Viruses causing chronic infection artfully manipulate infected cells to enable viral persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 (HTLV-1) establishes persistent infection mainly in CD4+ T cells in vivo and induces leukemia in this subset. HTLV-1–encoded Tax...

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Detalles Bibliográficos
Autores principales: Mahgoub, Mohamed, Yasunaga, Jun-ichirou, Iwami, Shingo, Nakaoka, Shinji, Koizumi, Yoshiki, Shimura, Kazuya, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819419/
https://www.ncbi.nlm.nih.gov/pubmed/29358408
http://dx.doi.org/10.1073/pnas.1715724115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819419/
https://www.ncbi.nlm.nih.gov/pubmed/29358408
http://dx.doi.org/10.1073/pnas.1715724115

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