Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling

Differentiated airway epithelia produce sonic hedgehog (SHH), which is found in the thin layer of liquid covering the airway surface. Although previous studies showed that vertebrate HH signaling requires primary cilia, as airway epithelia mature, the cells lose primary cilia and produce hundreds of...

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Detalles Bibliográficos
Autores principales: Mao, Suifang, Shah, Alok S., Moninger, Thomas O., Ostedgaard, Lynda S., Lu, Lin, Tang, Xiao Xiao, Thornell, Ian M., Reznikov, Leah R., Ernst, Sarah E., Karp, Philip H., Tan, Ping, Keshavjee, Shaf, Abou Alaiwa, Mahmoud H., Welsh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819449/
https://www.ncbi.nlm.nih.gov/pubmed/29358407
http://dx.doi.org/10.1073/pnas.1719177115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819449/
https://www.ncbi.nlm.nih.gov/pubmed/29358407
http://dx.doi.org/10.1073/pnas.1719177115

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