X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells

BACKGROUND: Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. To elucidate the genetic origins of sex-specific DNA methylation, we examined DN...

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Detalles Bibliográficos
Autores principales: Ho, Bianca, Greenlaw, Keelin, Al Tuwaijri, Abeer, Moussette, Sanny, Martínez, Francisco, Giorgio, Elisa, Brusco, Alfredo, Ferrero, Giovanni Battista, Linhares, Natália D., Valadares, Eugênia R., Svartman, Marta, Kalscheuer, Vera M., Rodríguez Criado, Germán, Laprise, Catherine, Greenwood, Celia M. T., Naumova, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819645/
https://www.ncbi.nlm.nih.gov/pubmed/29463315
http://dx.doi.org/10.1186/s13293-018-0169-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819645/
https://www.ncbi.nlm.nih.gov/pubmed/29463315
http://dx.doi.org/10.1186/s13293-018-0169-7

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