A simulation study on estimating biomarker–treatment interaction effects in randomized trials with prognostic variables

BACKGROUND: To individualize treatment decisions based on patient characteristics, identification of an interaction between a biomarker and treatment is necessary. Often such potential interactions are analysed using data from randomized clinical trials intended for comparison of two treatments. Tes...

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Detalles Bibliográficos
Autores principales: Haller, Bernhard, Ulm, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819679/
https://www.ncbi.nlm.nih.gov/pubmed/29463271
http://dx.doi.org/10.1186/s13063-018-2491-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819679/
https://www.ncbi.nlm.nih.gov/pubmed/29463271
http://dx.doi.org/10.1186/s13063-018-2491-0

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