Cargando…
Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity
OBJECTIVE: The Hairy Enhancer of Split 1 (HES1) is a transcriptional repressor that regulates cellular proliferation and differentiation during development. We previously found an interaction between HES1 and Fanconi anemia (FA) proteins. FA is a hematological and developmental disorder caused by mu...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819684/ https://www.ncbi.nlm.nih.gov/pubmed/29463306 http://dx.doi.org/10.1186/s13104-018-3243-7 |