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Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

BACKGROUND: Clinical complications associated with atherosclerotic plaques arise from luminal obstruction due to plaque growth or destabilization leading to rupture. We previously demonstrated that overexpression of insulin receptor isoform A (IRA) and insulin-like growth factor-I receptor (IGF-IR)...

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Detalles Bibliográficos
Autores principales: Beneit, Nuria, Martín-Ventura, José Luis, Rubio-Longás, Carlota, Escribano, Óscar, García-Gómez, Gema, Fernández, Silvia, Sesti, Giorgio, Hribal, Marta Letizia, Egido, Jesús, Gómez-Hernández, Almudena, Benito, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819698/
https://www.ncbi.nlm.nih.gov/pubmed/29463262
http://dx.doi.org/10.1186/s12933-018-0675-2