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Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

BACKGROUND: Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chemotherapy, transdifferentiation of plasma cell myeloma into myeloid neoplasms ha...

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Detalles Bibliográficos
Autores principales: Gralewski, Jonathon H., Post, Ginell R., van Rhee, Frits, Yuan, Youzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819706/
https://www.ncbi.nlm.nih.gov/pubmed/29463311
http://dx.doi.org/10.1186/s13000-018-0692-1