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Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation

BACKGROUND: Transwell-based models of the blood–brain barrier (BBB) incorporating monolayers of human brain microvascular endothelial cells (dhBMECs) derived from induced pluripotent stem cells show many of the key features of the BBB, including expression of transporters and efflux pumps, expressio...

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Detalles Bibliográficos
Autores principales: Katt, Moriah E., Linville, Raleigh M., Mayo, Lakyn N., Xu, Zinnia S., Searson, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819713/
https://www.ncbi.nlm.nih.gov/pubmed/29463314
http://dx.doi.org/10.1186/s12987-018-0092-7