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Treatment with combined dabrafenib and trametinib in BRAF(V600E)-mutated metastatic malignant melanoma: a case of long-term complete response after treatment cessation

Here, we report the case of a patient, diagnosed with BRAF(V600E)-mutated metastatic malignant melanoma M1a, who achieved a complete metabolic response after 7 months of treatment with the combination of dabrafenib and trametinib. After 31 months, the treatment was interrupted for patient’s decision...

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Detalles Bibliográficos
Autores principales: Brugnara, Sonia, Sicher, Mariacristina, Bonandini, Elena Maria, Donner, Davide, Chierichetti, Franca, Barbareschi, Mattia, Girardelli, Carlo Renè, Caffo, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819728/
https://www.ncbi.nlm.nih.gov/pubmed/29483930
http://dx.doi.org/10.7573/dic.212515