DNA methylation profiling of genomic DNA isolated from urine in diabetic chronic kidney disease: A pilot study

AIM: To characterise the genomic DNA (gDNA) yield from urine and quality of derived methylation data generated from the widely used Illuminia Infinium MethylationEPIC (HM850K) platform and compare this with buffy coat samples. BACKGROUND: DNA methylation is the most widely studied epigenetic mark an...

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Detalles Bibliográficos
Autores principales: Lecamwasam, Ashani, Sexton-Oates, Alexandra, Carmody, Jake, Ekinci, Elif I., Dwyer, Karen M., Saffery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819761/
https://www.ncbi.nlm.nih.gov/pubmed/29462136
http://dx.doi.org/10.1371/journal.pone.0190280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819761/
https://www.ncbi.nlm.nih.gov/pubmed/29462136
http://dx.doi.org/10.1371/journal.pone.0190280

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