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A Dendritic cell targeted vaccine induces long term HIV-specific immunity within the gastrointestinal tract

Despite significant therapeutic advances for HIV-1 infected individuals, a preventative HIV-1 vaccine remains elusive. Studies focusing on early transmission events, including the observation that there is a profound loss of gastrointestinal (GI) CD4(+) T cells during acute HIV-1 infection, highligh...

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Detalles Bibliográficos
Autores principales: Ruane, Darren, Do, Yoonkyung, Brane, Lucas, Garg, Aakash, Bozzacco, Leonia, Kraus, Thomas, Caskey, Marina, Salazar, Andres, Trumpheller, Christine, Mehandru, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819881/
https://www.ncbi.nlm.nih.gov/pubmed/26732678
http://dx.doi.org/10.1038/mi.2015.133