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GW4064 attenuates lipopolysaccharide-induced hepatic inflammation and apoptosis through inhibition of the Toll-like receptor 4-mediated p38 mitogen-activated protein kinase signaling pathway in mice

Liver injury is associated with devastating consequences caused by inflammation and apoptosis. The farnesoid X receptor (FXR) is a nuclear receptor that has an essential role in hepatoprotection by maintaining the homeostasis of liver metabolism. The present study investigated the capacity of the FX...

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Detalles Bibliográficos
Autores principales: Liu, Hsuan-Miao, Lee, Tzung-Yan, Liao, Jyh-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819900/
https://www.ncbi.nlm.nih.gov/pubmed/29328388
http://dx.doi.org/10.3892/ijmm.2018.3366